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The active component of the medication Priligy is Dapoxetine. Priligy is one of the medications in a group of medications called SSRIs (selective serotonin reuptake inhibitors). Priligy is also known as one of the urological medications. Priligy is taken by patients who want to control over their ejaculation. It actually increases the time it usually takes them to ejaculate. The medication is used to reduce the patients’ worry or frustration about fast ejaculation. So Priligyu is used when treating premature ejaculation in men of age range between eighteen up to sixty four years of age. What is premature ejaculation? It happens when a man can ejaculate even with even little sexual stimulation and not at the moment when a man wants but much before it. It can cause psychological problems in men and also problems in their sexual life and relationship with sexual partner.
Nowadays when you can buy Priligy online from a virtual drug store people should be twice attentive and responsible with their health. You should know lots of important things before you purchase Priligy and start taking it hoping to improve your sexual life.
So you shouldn’t take Priligy in case is you have allergy to its active component Diapoxetine or any other components Priligy contains (read the complete list in the list of recommendations coming with Priligy tablets). If you suffer from any heart problems including heart failure, problems with heart rhythm or in case you have a history of collapsing. Patients who have had mania or severe depression (feeling too much excited, not able to think clearly or irritable) are not allowed to take Priligy.
You shouldn’t take the medication Priligy with the following medications: MAOIs (monoamine oxidase inhibitors), Thioridazine, medications treating depression, Lithium medicines, antibiotic Linezolid, Tryptophan, Tramadol. If it is necessary for patients to treat with the mentioned above medications, they will need to wait for at least fourteen days after they stop taking these medications and only then start using Priligy. There are much more different medications which you cannot combine Priligy with. Ask your doctor for the full list. If you are not really sure about the time of taking Priligy and the listed medications, it is better to consult a pharmacist or your personal health provider. Never practice self-treatment!
When you buy and start using Priligy without prescription, you have to know that the medication shouldn’t be taken by women. Men taking this medication may feel dizzy or sleepy; have difficulties in concentrating, blurred vision, and faint. If a man feels any of these conditions, he should avoid driving and operating machinery. Priligy can also increase the effects of alcohol and so the risks of fainting or any other side effects of the medicine.
It is important to inform your personal doctor if you suffer from any sugar intolerance as Priligy contains lactose.
When you order Priligy online be very attentive as for the rules of its proper usage! Always take the medication exactly as it was told by your personal doctor! The usual dose of the medication is 30 mg. Sometimes a dose may be increased to 60 mg by your health provider. So take it one or three hours between a planned sexual activity. Don’t take the medication more often than once in 24 hours.
Possible side effects of Priligy are (though not all patients get them):
– fainting of feeling light-headed when standing up;
– changes in mood;
– self-harming or thoughts about commiting a suicide.
If you notice any of these effects, stop taking Priligy at once and seek for your doctor’s assistance. And do not forget to drink enough water when treating with Priligy in order not to suffer from dehydration.
So, just be attentive to your health and when you buy your cheap Priligy in an online pharmacy, it will bring you the desirable effect.
additional information Dapoxetine (Priligy)
Buy Dapoxetine Online Now to Prolong Your Sexual Pleasure
What Is Dapoxetine?
Generic Dapoxetine is a medication that solves one of the most important sexual problems – premature ejaculation (PE). The medicine is intended for use by male patients aged from 18 to 64 years old.
Premature Ejaculation Problem?
What Is Premature Ejaculation?
Ejaculation is the peak moment of the sexual activity. Sexual intercourse is supposed to end in ejaculation, a complicated biological process designed by nature for continuation of humankind. This term is closely connected with the following two phenomena that always accompany ejaculation: orgasm and semen release. Semen is intensively released and pulled out of the penis by a specific group of muscles to reach a female ovary in the long run. Orgasm is accompanied by the strongest pleasant feelings any man has ever experienced in his life.
Of course, every woman wants her man to stay sexually active as long as possible during sexual intercourse. And it usually takes a certain amount of time for a man to reach ejaculation. This time is specific for every man, but is not supposed to be less than a number set by medical experts. The scientific studies showed that an average man reaches ejaculation within 4-8 minutes, and that is a norm. If a person does not ejaculate within this time, it is time to think of such a possible problem as premature ejaculation. Premature here means early or rapid. Thus, premature ejaculation is sometimes called early ejaculation or rapid ejaculation.
There has been controversy among medical specialists about time threshold limit value that characterizes premature ejaculation sexual intercourse. However, the International Society for Sexual Medicine agreed on the point by defining premature ejaculation as occurring within a minute from the beginning of sexual intercourse. Nevertheless, according to the International Classification of Diseases, ejaculation is considered premature if it occurs within 15 seconds.
What causes PE?
Regardless of the knowledge that has been accumulated on PE, the underlying cause of this condition still remains unclear. The problem has aroused a lot of interest among scientists. As a result, many of them put forward their theories. According to one theorist, premature ejaculation may be the result of quick masturbation, a case when an adolescent has to ejaculate as soon as possible for fear of being caught by his mother. Another theorist supposed that a person who has little sex develops PE. There are many other theories like those mentioned above. But none of them has been confirmed.
Some scientists believe that a genetic factor plays a leading role in developing PE. According to the results of one study, more than 90% of male participants who have suffered from premature ejaculation during their lifetime had a close relative with chronic premature ejaculation.
According to other researchers, prostatitis may be the cause of PE. According to others, so may some drugs with specific side effects.
What Types of Premature Ejaculation Are There?
Before opting for a treatment solution, doctor should figure out whether premature ejaculation is a complaint or a syndrome. A man may experience the ejaculation problem as a temporary sexual disorder that goes away by itself after a lapse of a certain amount of time. The case is “natural variable PE”. A man can also be diagnosed with such a type of PE as “premature-like ejaculatory dysfunction” based on a set of tests and diagnostic measures. Those two types mentioned above have been proposed recently whereas two others – “lifelong PE” and “acquired PE” were introduced about half a century ago.
All of the types deal with such a term as IELT that stands for intravaginal ejaculation latency time. This indicator shows how long it takes a man to reach orgasm. According to current evidence, an average IELT for 18-30 year-old men is 6 minutes and 30 seconds. If a person ejaculates within two minutes on a regular basis, he certainly has PE.
If a man has had PE since his puberty, his PE is sometimes called primary premature ejaculation. If the condition began developing later in life, it is referred to as secondary PE.
If a person has difficulty ejaculating with certain partners, he has situational PE. And if he ejaculates too fast with any partner he has, he may experience global PE.
How Can PE Be Treated?
PE treatment depends on the type of the condition and IELT. In case of lifelong PE a person should be given specific medications as a first treatment option if his IELT is less than 1-1.5 minutes.
Other PE types may also imply such treatment approaches as behavior therapy, patient reassurance, or psychoeducation focusing on the idea of PE as a natural normal variation when it occurs irregularly.
The best approach is to combine both medication and non-medication treatments. Medications used for treating PE may include such SSRIs as paroxetine, clomipramine as well as tramadol and, of course, dapoxetine.
What Is SSRI?
Dapoxetine belongs to a big group of medications collectively called SSRIs (standing for selective serotonin re-uptake inhibitors). SSRIs are typically intended for use by people with depression, personality disorders, and anxiety disorders.
As appears from its name, the action of SSRI involves serotonin, a neurotransmitter that participates in the regulation of mood, sleep, and appetite.
The action of any SSRI is based on the increase in the extracellular serotonin. This happens because of its reuptake into the presynaptic cell. Those complicated processes are reflected in the name of the group of medications we are now talking about.
SSRIs are considered to be psychotropic drugs that are capable of affecting person’s mood and thoughts. That is why they are widely used for treating depression. Frankly speaking, this category of medicines is the most commonly prescribed when it comes to fighting depressive condition. However, their effectiveness is sometimes questioned. Besides, a lot of SSRIs are associated with side effects that are, however, typically mild and harmless.
How Does Dapoxetine Work?
Generally speaking, Dapoxetine affects the way various areas in the CNS regulate ejaculation. It’s a complex process that consists of a number of stages.
The process starts with a spinal reflex at a certain level of spinal cord generated by stimuli from genital. The brain stem then receives these signals. The process is then affected by medial preoptic and paraventricular nuclei in the brain. It has been shown by studies that when administrated orally, Dapoxetine acts by inhibiting ejaculatory expulsion reflex through a sophisticated modulation mechanism that involves so-called LPGi neurons. As a result, PMRD (pudendal motoneuron reflex discharge) latency increases.
How Can Dapoxetine Be Synthesized?
Nowadays S-Dapoxetine can be synthesized using a few methods. The most common of them, which is a new phenomenon in the industry as well, includes 6 stages. Let’s consider 3 of them that play the most important role in obtaining the final substance.
Trans cinnamyl alcohol is the starting point in the synthesis process. This substance can be purchased. S-Dapoxetine is finally obtained as a result of sharpless asymmetric epoxidation and Mitsunobu reaction.
The method is looked upon as a good solution thanks to high yield (more than 35%) and get-at-able reactants.
When Is Maximum Effect of Dapoxetine Achieved?
To begin with, dapoxetine comes in white powder that easily dissolves in water. The active substance of the medicine immediately gets into the bloodstream and is absorbed fast. It is most optimal to take Dapoxetine 1-2 hours prior to sexual intercourse because it takes the medicine this amount of time to reach its maximum plasma concentration (Cm). Cm can be slightly reduced by high fat foods. However, this reduction is very small. Thus, the action of dapoxetine is not affected by food. So, you can take the medication with or without food.
Is Dapoxetine Safe & Easily Tolerated?
First of all, it is important to take into account a cardiovascular aspect. In other words, is Dapoxetine safe for a cardiovascular system and especially for its central component – the heart? One study showed that even if the dose is 4-fold greater than a maximum one (60 mg), the medicine does not present any cardiovascular risks.
Another safety aspect involves neurocognitive reaction to Dapoxetine. The studies that involved other SSRIs showed that they may cause such adverse effects as suicidal thoughts, changes in mood, anxiety, hypomania. However, there is no evidence that Dapoxetine has the same side effects.
Dapoxetine is gaining more and more popularity as the number of men with PE is constantly increasing. The medication is currently available in fifty countries and this is not going to be confined to that number. During two years – in 2009 and 2010 – Dapoxetine was approved in such countries as Mexico, Italy, Spain, New Zealand, and South Korea. Some time later the list was widened with Philippines, France, Malaysia, Uruguay, and Argentina. Nowadays Dapoxetine is marketed in such countries as Austria, Sweden, Finland, Germany, Portugal, Spain, and Italy.
How Should Dapoxetine Be Properly Used?
First of all, before you purchase Dapoxetine you should make sure that the medicine won’t do you any harm. So, you need to check with your doctor who will make his conclusion after a physical examination or maybe a number of tests. To help your doctor in his decision making process, you should provide the medical specialist with your medical history as well as you should draw his attention to your current condition. If your doctor approves of your treatment with Dapoxetine, it should entirely be based on your doctor’s professional advice. That means that you will get a Dapoxetine prescription you should stringently follow. Only in this case your safety is entirely ensured. Such an approach should be applied when you take any other medication.
There are two pill weight options of Dapoxetine – 30 and 60 mg. The maximum recommended dose a day is 60 mg. Your doctor should specify your dosage in the prescription paper, as well as your schedule and the length of treatment.
What Are Dapoxetine Contraindications
Before you order Dapoxetine online from our Dapoxetine online pharmacy, you should understand that the medicine has certain contraindications. If a medicine is contraindicated, this means that it should not be used for some reason, or the medication may do harm to patient’s health.
Since liver plays a key role in the metabolism of Dapoxetine, it is inadmissible for a male patient with hepatic impairment (from moderate to severe) to take the medicine.
A person who suffers from heart failure or has a pacemaker should never take Dapoxetine.
The medicine should not be taken by people who are taking ketoconazole, ritonavir, or telithromycine. Ask your doctor whether you can safely take the medicine or not if you are taking thioridazine, serotonin-norepinephrine reuptake inhibitors, SSRIs, monoamine oxidase inhibitors, or tricyclic antidepressant. If you have stopped taking any of the above-mentioned medications, it is necessary to wait for 2 weeks before getting started with Dapoxetine. And vice versa – if you have stopped Dapoxetine treatment and are going to get started with any of the foregoing medications, you should wait for a week before using the first dose of any of them. You should keep that in mind before purchasing Dapoxetine online.
Does Dapoxetine Interact With Sildenafil or Tadalafil?
Sildenafil (Viagra) and tadalafil (Cialis) are the two most common substances used in the formulas of popular medications for treating erectile dysfunction. The results of numerous studies showed that there is no harmful interaction between Dapoxetine and any of the most popular ED medications.
Does Dapoxetine Interact With Ethanol?
Taken concurrently with Dapoxetine, ethanol does not enter into any harmful interaction. This has been shown by a number of independent studies.
What Are Possible Side Effects of Dapoxetine?
Before you buy Dapoxetine online, you should realize that you can encounter some side effects. Most of them are harmless and experienced by many patients. So, the following mild effects are rather common:
• dry mouth;
Regardless of a close connection between the use of SSRIs and high incidences of sexual dysfunction, there is no scientific evidence that Dapoxetine causes sexual dysfunction.
What Is the History of Dapoxetine?
It is an interesting fact that Dapoxetine was originally developed as an antidepressant. Unfortunately for Eli Lilly who created the medicine, clinical trials of the medicine met with failure – Dapoxetine showed low effectiveness in treating depression. The medicine had been forgotten and shelved for a while until the research work on its PE-fighting formula was renewed and continued. It was in December, 2003 that patent of Dapoxetine was sold by Eli Lilly to PPD (Pharmaceutical Product Development).Nowadays Alza owns Dapoxetine.
Where Can You Buy Dapoxetine?
You can order Dapoxetine right here and right now without wasting time and extra money. Our pharmacy offers a great variety of medicines at attractive prices. We have been providing our customers with high-quality medicines for many years, and now we have a big client base. We are committed to maintaining such a level of our customers’ loyalty through fair prices and first-class service.
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